6 research outputs found

    An explicit Nash equilibrium for a market share attraction game

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    In competitive marketing, the speed of generating the best price has become as critical as its reliability. In this study, we aim to design a practical marketing management tool. We consider a non-cooperative marketing environment with multiple substitute products, where total market size is moderately price-sensitive. The price-demand relations are determined by a market share attraction model, where the attraction of each product is a linear function of its price. The product's brand image is reflected in the parameters of this linear function. For the general case of multiple substitute products, we derive explicit expressions for the best-response functions. For the specific case of two substitute products, we derive closed form expressions for the prices at Nash equilibrium. These expressions help managers in changing their marketing instruments other than price, so as to obtain substantial individual profits. We show how our closed form Nash equilibrium enables the examination of the profit loss due to competition. Relevant for practice is the fact that our model can be easily calibrated. We provide a simple procedure for estimating the model parameters

    The Relationship of the Peroxisome Proliferator Activated ReceptorGamma 2 Exon 2 and Exon 6 Gene Polymorphism in Type 2 Diabetic Patients with and without Diabetic Foot Ulcers

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    We aims investigate Turkish type 2 diabetic patients with/without diabetic foot ulcers and healthy group and examined the contribution of the G/C exon 2 and T/C exon 6 of the PPARgamma gene polymorphism to the development of diabetic foot ulcers. The PPARgamma genotypes were determined prospectively in 50 patients with diabetic foot ulcers and 50 without diabetic foot ulcers and a control group of 50 healthy individuals. Genotyping of the G/C exon 2 and T/C exon 6 of the PPAR-gamma gene polymorphism for all individuals was performed by melting curve analysis of the generated amplicons after real-time online PCR. The genotype exon 2 and exon 6 distribution did not differ between the control group and the type 2 diabetes mellitus patients (with and without diabetic foot) (P>0.05). The frequency of the polymorphic G allele in exon 2 was no similar for the groups (6% and 1%, respectively) (p0.05). The evaluation of exon 2 and exon 6, genotype and haplotype did not show statistically significant difference between the patient diabetic foot and without diabetic foot (p>0.05). The G/C exon 2 and T/C exon 6 of the PPARgamma gene polymorphism is not an independent risk factor for diabetic foot in Turkish type 2 diabetes mellitus patients. Genetic factors in the pathogenesis of diabetic foot may also show any changes in different populations. [Med-Science 2014; 3(4.000): 1582-94

    Medicine Science 2014;3(4):1582-94 Peroxisome Proliferator-Activated Receptor-Gamma 2 Gene Polymorphism in diabetic Foot Ulcers Original Investigation The Relationship of the Peroxisome Proliferator Activated Receptor-Gamma 2 Exon 2 and Exon 6 Gene Polymo

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    Abstract We aims investigate Turkish type 2 diabetic patients with/without diabetic foot ulcers and healthy group and examined the contribution of the Pro12Ala exon 2 and C478T exon 6 of th
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